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Methods to assess monitor and control bacterial biofilms

Résumé : The present disclosure describes methods for detecting, monitoring, and modulating (e.g., promoting, enhancing, sustaining, maintaining, reducing, mitigating or eliminating of) biofilm formation, as well as mitigating or eliminating Microbial Influenced Corrosion (MIC) of a metal surface. The method of monitoring includes: providing a test sample; detecting at least one of a prophage gene, a prophage gene expression, a prophage gene transcript, a prophage protein, a prophage metabolite, a prophage intermediate, or a combination thereof, wherein the existence, amount or level of prophage gene expression, a prophage gene transcript, a prophage protein, a prophage metabolite, a prophage intermediate, or a combination thereof relative to a control is indicative of biofilm presence, formation or the state of the biofilm in a sample. The present disclosure also describes a composition for modulating biofilm formation, maintenance, mitigation, reduction, and elimination.
Domaine de référence : Biocorrosion
Auteur Pilloni Giovanni, CHATTERJEE Mohor, He Kuang
Année de parution : 2018.
Mots-clés : bacteria, biofilm, gene, prophage, repressor.
Type de document : Brevet.
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Ce projet est financé par le Fonds Européen de Développement Régional, la Région Normandie et le Conseil Départemental de la Manche.