Résumé : Monopiles are the most common type of foundation used for bottom-fixed offshore wind turbines. This investigation concerns the influence of uncertainty related to soil–structure interaction models used to represent monopile–soil systems. The system response is studied for a severe sea state. Three wave-load cases are considered: (i) irregular waves assuming linearity; (ii) highly nonlinear waves that are merged into the irregular wave train; (iii) slamming loads that are included for the nonlinear waves. The extreme response and Fourier amplitude spectra for external moments and mudline bending moments are compared for these load cases where a simpler static pile-cap stiffness and a lumped-parameter model (LPM) are both considered. The fundamental frequency response of the system is well represented by the static pile-cap stiffness model; however, the influence of higher modes (i.e., the second and third modes with frequencies of about 1 Hz and 2 Hz, respectively) is significantly overestimated with the static model compared to the LPM. In the analyzed case, the differences in the higher modes are especially pronounced when slamming loads are not present.